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β-Catenin is a pH sensor with decreased stability at higher intracellular pH

β-Catenin functions as an adherens junction protein for cell–cell adhesion and as a signaling protein. β-catenin function is dependent on its stability, which is regulated by protein–protein interactions that stabilize β-catenin or target it for proteasome-mediated degradation. In this study, we sho...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: White, Katharine A., Grillo-Hill, Bree K., Esquivel, Mario, Peralta, Jobelle, Bui, Vivian N., Chire, Ismahan, Barber, Diane L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219716/
https://ncbi.nlm.nih.gov/pubmed/30315137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201712041
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