The Fab1/PIKfyve Phosphoinositide Phosphate Kinase Is Not Necessary to Maintain the pH of Lysosomes and of the Yeast Vacuole

Lysosomes and the yeast vacuole are degradative and acidic organelles. Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P(2)), a master architect of endolysosome and vacuole identity, is thought to be necessary for vacuolar acidification in yeast. There is also evidence that PtdIns(3,5)P(2) may pla...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ho, Cheuk Y., Choy, Christopher H., Wattson, Christina A., Johnson, Danielle E., Botelho, Roberto J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392288/
https://ncbi.nlm.nih.gov/pubmed/25713145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.613984
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