ADP Ribosylation Factor 6 (ARF6) Promotes Acrosomal Exocytosis by Modulating Lipid Turnover and Rab3A Activation

Regulated secretion is a central issue for the specific function of many cells; for instance, mammalian sperm acrosomal exocytosis is essential for egg fertilization. ARF6 (ADP-ribosylation factor 6) is a small GTPase implicated in exocytosis, but its downstream effectors remain elusive in this proc...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Pelletán, Leonardo E., Suhaiman, Laila, Vaquer, Cintia C., Bustos, Matías A., De Blas, Gerardo A., Vitale, Nicolas, Mayorga, Luis S., Belmonte, Silvia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392280/
https://ncbi.nlm.nih.gov/pubmed/25713146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.629006
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