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Sphingosine 1-Phosphate and Sphingosine Kinase Are Involved in a Novel Signaling Pathway Leading to Acrosomal Exocytosis

Regulated secretion is a central issue for the specific function of many cells; for instance, mammalian sperm acrosomal exocytosis is essential for egg fertilization. Sphingosine 1-phosphate is a bioactive sphingolipid that regulates crucial physiological processes. Here we report that this lipid tr...

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Detalhes bibliográficos
Main Authors: Suhaiman, Laila, De Blas, Gerardo A., Obeid, Lina M., Darszon, Alberto, Mayorga, Luis S., Belmonte, Silvia A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871498/
https://ncbi.nlm.nih.gov/pubmed/20236935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.072439
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