Sestrin 2 Protein Regulates Platelet-derived Growth Factor Receptor β (Pdgfrβ) Expression by Modulating Proteasomal and Nrf2 Transcription Factor Functions

We recently identified the antioxidant protein Sestrin 2 (Sesn2) as a suppressor of platelet-derived growth factor receptor β (Pdgfrβ) signaling and Pdgfrβ signaling as an inducer of lung regeneration and injury repair. Here, we identified Sesn2 and the antioxidant gene inducer nuclear factor erythr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tomasovic, Ana, Kurrle, Nina, Sürün, Duran, Heidler, Juliana, Husnjak, Koraljka, Poser, Ina, Schnütgen, Frank, Scheibe, Susan, Seimetz, Michael, Jaksch, Peter, Hyman, Anthony, Weissmann, Norbert, von Melchner, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392273/
https://ncbi.nlm.nih.gov/pubmed/25716320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.632133
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