Plasminogen Activator Inhibitor-1 Suppresses Profibrotic Responses in Fibroblasts from Fibrotic Lungs

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease characterized by progressive interstitial scarification. A hallmark morphological lesion is the accumulation of myofibroblasts or fibrotic lung fibroblasts (FL-fibroblasts) in areas called fibroblastic foci. We previously demonstrated that...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Marudamuthu, Amarnath S., Shetty, Shwetha K., Bhandary, Yashodhar P., Karandashova, Sophia, Thompson, Michael, Sathish, Venkatachalem, Florova, Galina, Hogan, Taryn B., Pabelick, Christina M., Prakash, Y. S., Tsukasaki, Yoshikazu, Fu, Jian, Ikebe, Mitsuo, Idell, Steven, Shetty, Sreerama
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392249/
https://ncbi.nlm.nih.gov/pubmed/25648892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.601815
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