Plasminogen Activator Inhibitor-1 Suppresses Profibrotic Responses in Fibroblasts from Fibrotic Lungs

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease characterized by progressive interstitial scarification. A hallmark morphological lesion is the accumulation of myofibroblasts or fibrotic lung fibroblasts (FL-fibroblasts) in areas called fibroblastic foci. We previously demonstrated that...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Marudamuthu, Amarnath S., Shetty, Shwetha K., Bhandary, Yashodhar P., Karandashova, Sophia, Thompson, Michael, Sathish, Venkatachalem, Florova, Galina, Hogan, Taryn B., Pabelick, Christina M., Prakash, Y. S., Tsukasaki, Yoshikazu, Fu, Jian, Ikebe, Mitsuo, Idell, Steven, Shetty, Sreerama
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392249/
https://ncbi.nlm.nih.gov/pubmed/25648892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.601815
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