Additive effects of HLA alleles and innate immune genes determine viral outcome in HCV infection

BACKGROUND: Chronic HCV infection is a leading cause of liver-related morbidity globally. The innate and adaptive immune responses are thought to be important in determining viral outcomes. Polymorphisms associated with the IFNL3 (IL28B) gene are strongly associated with spontaneous clearance and tr...

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Bibliografske podrobnosti
izdano v:Gut
Main Authors: Fitzmaurice, Karen, Hurst, Jacob, Dring, Megan, Rauch, Andri, McLaren, Paul J, Günthard, Huldrych F, Gardiner, Clair, Klenerman, Paul
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2015
Teme:
Hepatology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392199/
https://ncbi.nlm.nih.gov/pubmed/24996883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-306287
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