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Additive effects of HLA alleles and innate immune genes determine viral outcome in HCV infection

BACKGROUND: Chronic HCV infection is a leading cause of liver-related morbidity globally. The innate and adaptive immune responses are thought to be important in determining viral outcomes. Polymorphisms associated with the IFNL3 (IL28B) gene are strongly associated with spontaneous clearance and tr...

詳細記述

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書誌詳細
出版年:Gut
主要な著者: Fitzmaurice, Karen, Hurst, Jacob, Dring, Megan, Rauch, Andri, McLaren, Paul J, Günthard, Huldrych F, Gardiner, Clair, Klenerman, Paul
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392199/
https://ncbi.nlm.nih.gov/pubmed/24996883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-306287
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