Additive effects of HLA alleles and innate immune genes determine viral outcome in HCV infection

BACKGROUND: Chronic HCV infection is a leading cause of liver-related morbidity globally. The innate and adaptive immune responses are thought to be important in determining viral outcomes. Polymorphisms associated with the IFNL3 (IL28B) gene are strongly associated with spontaneous clearance and tr...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Fitzmaurice, Karen, Hurst, Jacob, Dring, Megan, Rauch, Andri, McLaren, Paul J, Günthard, Huldrych F, Gardiner, Clair, Klenerman, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Hepatology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392199/
https://ncbi.nlm.nih.gov/pubmed/24996883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-306287
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