IKKβ in postnatal perichondrium remotely controls endochondral ossification of the growth plate through downregulation of MCP-5

IκB kinase β (IKKβ) is a catalytic subunit of the IKK complex, which activates nuclear factor-κB (NF-κB). Although its role in osteoclastogenesis is well established, the role of IKKβ in bone formation is poorly understood. Here, we report that conditional knockout of Ikkβ in limb bud mesenchymal ce...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Differ
Asıl Yazarlar: Kobayashi, K, Toguchida, J, Karin, M, Kato, T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392083/
https://ncbi.nlm.nih.gov/pubmed/25526093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.192
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