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Relationship between protein thermodynamic constraints and variation of evolutionary rates among sites

Evolutionary-rate variation among sites within proteins depends on functional and biophysical properties that constrain protein evolution. It is generally accepted that proteins must be able to fold stably in order to function. However, the relationship between stability constraints and among-sites...

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Bibliografiske detaljer
Udgivet i:Phys Biol
Main Authors: Echave, Julian, Jackson, Eleisha L., Wilke, Claus O.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391963/
https://ncbi.nlm.nih.gov/pubmed/25787027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/12/2/025002
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