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The Relationship Between Relative Solvent Accessibility and Evolutionary Rate in Protein Evolution
Recent work with Saccharomyces cerevisiae shows a linear relationship between the evolutionary rate of sites and the relative solvent accessibility (RSA) of the corresponding residues in the folded protein. Here, we aim to develop a mathematical model that can reproduce this linear relationship. We...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Genetics Society of America
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122320/ https://ncbi.nlm.nih.gov/pubmed/21467571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.128025 |
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