Role of central and peripheral opiate receptors in the effects of fentanyl on analgesia, ventilation and arterial blood-gas chemistry in conscious rats

This study determined the effects of the peripherally restricted µ-opiate receptor (µ-OR) antagonist, naloxone methiodide (NLXmi) on fentanyl (25 µg/kg, i.v.)-induced changes in (1) analgesia, (2) arterial blood gas chemistry (ABG) and alveolar-arterial gradient (A-a gradient), and (3) ventilatory p...

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Bibliografiske detaljer
Udgivet i:Respir Physiol Neurobiol
Main Authors: Henderson, Fraser, May, Walter J., Gruber, Ryan B., Discala, Joseph F., Puscovic, Veljko, Young, Alex P., Baby, Santhosh M., Lewis, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391496/
https://ncbi.nlm.nih.gov/pubmed/24284037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2013.11.005
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