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Translation regulation and proteasome mediated degradation cooperate to keep Stem-loop binding protein, a major player in histone mRNA metabolism, low in G1-phase
Histone mRNA levels are cell cycle regulated, and the major regulatory steps are at the posttranscriptional level. A major regulatory mechanism is S- phase restriction of Stem-loop binding protein (SLBP) which binds to the 3′ end of histone mRNA and participates in multiple steps of histone mRNA met...
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| Veröffentlicht in: | J Cell Biochem |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4391495/ https://ncbi.nlm.nih.gov/pubmed/24122909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24686 |
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