The Stem-Loop Binding Protein Is Required for Efficient Translation of Histone mRNA In Vivo and In Vitro

Metazoan replication-dependent histone mRNAs end in a conserved stem-loop rather than in the poly(A) tail found on all other mRNAs. The 3′ end of histone mRNA binds a single class of proteins, the stem-loop binding proteins (SLBP). In Xenopus, there are two SLBPs: xSLBP1, the homologue of the mammal...

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Bibliographic Details
Main Authors: Sànchez, Ricardo, Marzluff, William F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC139811/
https://ncbi.nlm.nih.gov/pubmed/12242288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7093-7104.2002
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