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Coordinate regulation of histone mRNA metabolism and DNA replication: Cyclin A/cdk1 is involved in inactivation of histone mRNA metabolism and DNA replication at the end of S phase

S phase is characterized by the replication of DNA and assembly of chromatin. This requires the synthesis of large amounts of histone proteins to package the newly replicated DNA. Histone mRNAs are the only mRNAs that do not have polyA tails, ending instead in a conserved stemloop sequence. The stem...

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Autori principali: Koseoglu, M Murat, Dong, Jian, Marzluff, William F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047749/
https://ncbi.nlm.nih.gov/pubmed/20935461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.19.13300
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