MYB Elongation Is Regulated by the Nucleic Acid Binding of NFκB p50 to the Intronic Stem-Loop Region

MYB transcriptional elongation is regulated by an attenuator sequence within intron 1 that has been proposed to encode a RNA stem loop (SLR) followed by a polyU tract. We report that NFκBp50 can bind the SLR polyU RNA and promote MYB transcriptional elongation together with NFκBp65. We identified a...

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Pubblicato in:PLoS One
Autori principali: Pereira, Lloyd A., Hugo, Honor J., Malaterre, Jordane, Huiling, Xu, Sonza, Secondo, Cures, Alina, Purcell, Damian F. J., Ramsland, Paul A., Gerondakis, Steven, Gonda, Thomas J., Ramsay, Robert G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390348/
https://ncbi.nlm.nih.gov/pubmed/25853889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122919
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