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Estrogen receptor-α recruits P-TEFb to overcome transcriptional pausing in intron 1 of the MYB gene
The MYB proto-oncogene is expressed in most estrogen receptor-positive (ERα(+)) breast tumors and cell lines. Expression of MYB is controlled, in breast cancer and other cell types, by a transcriptional pausing mechanism involving an attenuation site located ∼1.7 kb downstream from the transcription...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401469/ https://ncbi.nlm.nih.gov/pubmed/22492511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks286 |
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