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HMGA1 recruits CTIP2-repressed P-TEFb to the HIV-1 and cellular target promoters
Active positive transcription elongation factor b (P-TEFb) is essential for cellular and human immunodeficiency virus type 1 (HIV-1) transcription elongation. CTIP2 represses P-TEFb activity in a complex containing 7SK RNA and HEXIM1. Recently, the inactive 7SK/P-TEFb small nuclear RNP (snRNP) has b...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4005653/ https://ncbi.nlm.nih.gov/pubmed/24623795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku168 |
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