Therapeutic DNA vaccination against colorectal cancer by targeting the MYB oncoprotein

Cancers can be addicted to continued and relatively high expression of nuclear oncoproteins. This is evident in colorectal cancer (CRC) where the oncoprotein and transcription factor MYB is over expressed and essential to continued proliferation and tumour cell survival. Historically, targeting tran...

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Vydáno v:Clin Transl Immunology
Hlavní autoři: Cross, Ryan S, Malaterre, Jordane, Davenport, Alexander J, Carpinteri, Sandra, Anderson, Robin L, Darcy, Phillip K, Ramsay, Robert G
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318491/
https://ncbi.nlm.nih.gov/pubmed/25671128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2014.29
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