Therapeutic DNA vaccination against colorectal cancer by targeting the MYB oncoprotein

Cancers can be addicted to continued and relatively high expression of nuclear oncoproteins. This is evident in colorectal cancer (CRC) where the oncoprotein and transcription factor MYB is over expressed and essential to continued proliferation and tumour cell survival. Historically, targeting tran...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Cross, Ryan S, Malaterre, Jordane, Davenport, Alexander J, Carpinteri, Sandra, Anderson, Robin L, Darcy, Phillip K, Ramsay, Robert G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318491/
https://ncbi.nlm.nih.gov/pubmed/25671128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2014.29
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