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Using a Sequential Regimen to Eliminate Bacteria at Sublethal Antibiotic Dosages

We need to find ways of enhancing the potency of existing antibiotics, and, with this in mind, we begin with an unusual question: how low can antibiotic dosages be and yet bacterial clearance still be observed? Seeking to optimise the simultaneous use of two antibiotics, we use the minimal dose at w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Biol
Hauptverfasser: Fuentes-Hernandez, Ayari, Plucain, Jessica, Gori, Fabio, Pena-Miller, Rafael, Reding, Carlos, Jansen, Gunther, Schulenburg, Hinrich, Gudelj, Ivana, Beardmore, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390231/
https://ncbi.nlm.nih.gov/pubmed/25853342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002104
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