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Antibiotic combination efficacy (ACE) networks for a Pseudomonas aeruginosa model

The spread of antibiotic resistance is always a consequence of evolutionary processes. The consideration of evolution is thus key to the development of sustainable therapy. Two main factors were recently proposed to enhance long-term effectiveness of drug combinations: evolved collateral sensitiviti...

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Veröffentlicht in:PLoS Biol
Hauptverfasser: Barbosa, Camilo, Beardmore, Robert, Schulenburg, Hinrich, Jansen, Gunther
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945231/
https://ncbi.nlm.nih.gov/pubmed/29708964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2004356
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