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Evolutionary stability of collateral sensitivity to antibiotics in the model pathogen Pseudomonas aeruginosa

Evolution is at the core of the impending antibiotic crisis. Sustainable therapy must thus account for the adaptive potential of pathogens. One option is to exploit evolutionary trade-offs, like collateral sensitivity, where evolved resistance to one antibiotic causes hypersensitivity to another one...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Barbosa, Camilo, Römhild, Roderich, Rosenstiel, Philip, Schulenburg, Hinrich
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881144/
https://ncbi.nlm.nih.gov/pubmed/31658946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51481
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