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Testing the optimality properties of a dual antibiotic treatment in a two-locus, two-allele model

Mathematically speaking, it is self-evident that the optimal control of complex, dynamical systems with many interacting components cannot be achieved with ‘non-responsive’ control strategies that are constant through time. Although there are notable exceptions, this is usually how we design treatme...

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Main Authors: Peña-Miller, Rafael, Fuentes-Hernandez, Ayari, Reding, Carlos, Gudelj, Ivana, Beardmore, Robert
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032525/
https://ncbi.nlm.nih.gov/pubmed/24812050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2013.1035
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