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The optimal deployment of synergistic antibiotics: a control-theoretic approach

Medical and pharmacological communities have long searched for antimicrobial drugs that increase their effect when used in combination, an interaction known as synergism. These drug combinations, however, impose selective pressures in favour of multi-drug resistance and as a result, the benefit of s...

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Библиографические подробности
Главные авторы: Peña-Miller, Rafael, Lähnemann, David, Schulenburg, Hinrich, Ackermann, Martin, Beardmore, Robert
Формат: Artigo
Язык:Inglês
Опубликовано: The Royal Society 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427526/
https://ncbi.nlm.nih.gov/pubmed/22628215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2012.0279
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