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The optimal deployment of synergistic antibiotics: a control-theoretic approach

Medical and pharmacological communities have long searched for antimicrobial drugs that increase their effect when used in combination, an interaction known as synergism. These drug combinations, however, impose selective pressures in favour of multi-drug resistance and as a result, the benefit of s...

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Detalhes bibliográficos
Main Authors: Peña-Miller, Rafael, Lähnemann, David, Schulenburg, Hinrich, Ackermann, Martin, Beardmore, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427526/
https://ncbi.nlm.nih.gov/pubmed/22628215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2012.0279
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