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Beyond Mitophagy: Cytosolic PINK1 as a Messenger of Mitochondrial Health

Significance: Disruptions in mitochondrial homeostasis are implicated in human diseases across the lifespan. Recessive mutations in PINK1, which encodes the mitochondrially targeted PTEN-induced putative kinase 1 (PINK1), cause an autosomal recessive form of Parkinson's disease. As with all kin...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Steer, Erin K., Dail, Michelle K., Chu, Charleen T.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390087/
https://ncbi.nlm.nih.gov/pubmed/25557302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.6206
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