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A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease
The PTEN-induced putative kinase 1 (PINK1) is a mitochondrially targeted serine–threonine kinase, which is linked to autosomal recessive familial parkinsonism. Current literature implicates PINK1 as a pivotal regulator of mitochondrial quality control, promoting maintenance of respiring mitochondria...
में बचाया:
| मुख्य लेखक: | |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875056/ https://ncbi.nlm.nih.gov/pubmed/20385539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq143 |
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