LR1 regulates c-myc transcription in B-cell lymphomas.
LR1 is a 106-kDa sequence-specific DNA-binding protein first identified as a potential regulator of immunoglobulin class switch recombination in B lymphocytes. Here we report that LR1 binds to a site 310 nt upstream of the human c-myc P1 promoter. Mutation of this site decreases reporter gene expres...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
1994
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43900/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8197157/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.11.4915 |
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