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LR1 regulates c-myc transcription in B-cell lymphomas.

LR1 is a 106-kDa sequence-specific DNA-binding protein first identified as a potential regulator of immunoglobulin class switch recombination in B lymphocytes. Here we report that LR1 binds to a site 310 nt upstream of the human c-myc P1 promoter. Mutation of this site decreases reporter gene expres...

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Main Authors: Brys, A, Maizels, N
格式: Artigo
語言:Inglês
出版: 1994
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC43900/
https://ncbi.nlm.nih.gov/pubmed/8197157
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