AntiCD3Fv fused to human interleukin-3 deletion variant redirected T cells against human acute myeloid leukemic stem cells

BACKGROUND: Leukemic stem cells (LSCs) are frequently seen as a cause of treatment failure and relapse in patients with acute myeloid leukemia (AML). Thus, successful new therapeutic strategies for the treatment of AML should aim at eradicating LSCs. The identification of targets on the cell surface...

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Detaylı Bibliyografya
Yayımlandı:J Hematol Oncol
Asıl Yazarlar: Fan, Dongmei, Li, Zhenzhen, Zhang, Xiaolong, Yang, Yuqi, Yuan, Xiangfei, Zhang, Xiuli, Yang, Ming, Zhang, Yizhi, Xiong, Dongsheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389834/
https://ncbi.nlm.nih.gov/pubmed/25879549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0109-5
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