E1A-engineered human umbilical cord mesenchymal stem cells as carriers and amplifiers for adenovirus suppress hepatocarcinoma in mice

Gene therapy is an attractive approach for hepatocellular carcinoma (HCC) patients. Nevertheless, efficient transgene delivery remains a challenge. In this study, we explored a new targeted system based on human umbilical cord-derived mesenchymal stem cells (HUMSCs), which were engineered to deliver...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Zhenzhen, Ye, Zhou, Zhang, Xiaolong, Zhang, Qing, Fan, Dongmei, Zhang, Yanjun, Luo, Hongbo R., Yuan, Xiangfei, Li, Zongfang, Xiong, Dongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239516/
https://ncbi.nlm.nih.gov/pubmed/27322080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10122
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