Fmoc-Conjugated PEG-Vitamin E(2) Micelles for Tumor-Targeted Delivery of Paclitaxel: Enhanced Drug-Carrier Interaction and Loading Capacity

The purpose of this study is to develop an improved drug delivery system for enhanced paclitaxel (PTX) loading capacity and formulation stability based on PEG(5K)-(vitamin E)(2) (PEG(5K)-VE(2)) system. PEG(5K)-(fluorenylmethoxycarbonyl)-(vitamin E)(2) (PEG(5K)-FVE(2)) was synthesized using lysine as...

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Enregistré dans:
Détails bibliographiques
Publié dans:AAPS J
Auteurs principaux: Zhang, Yifei, Huang, Yixian, Zhao, Wenchen, Lu, Jianqin, Zhang, Peng, Zhang, Xiaolan, Li, Jiang, Gao, Xiang, Venkataramanan, Raman, Li, Song
Format: Artigo
Langue:Inglês
Publié: Springer US 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389742/
https://ncbi.nlm.nih.gov/pubmed/25193267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9651-2
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