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Effects of caffeine and its metabolite paraxanthine on intracranial self-stimulation in male rats

Caffeine is the most widely used psychostimulant in the world, though preclinical studies suggest weaker evidence for abuse-related effects than stimulants with high abuse liability, such as amphetamine or cocaine. Intracranial self-stimulation (ICSS) is one procedure used to assess the abuse liabil...

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Detalhes bibliográficos
Publicado no:Exp Clin Psychopharmacol
Main Authors: Lazenka, Matthew F., Moeller, F Gerard, Negus, S. Stevens
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389645/
https://ncbi.nlm.nih.gov/pubmed/25844631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/pha0000012
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