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Activation of a paramyxovirus fusion protein is modulated by inside-out signaling from the cytoplasmic tail

Many viruses have evolved fusion-mediating glycoproteins that couple the energy released from irreversible protein refolding to the work of membrane fusion. The viral fusion proteins require a triggering event to undergo a cascade of tightly regulated conformational changes. Different isolates of th...

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Detalles Bibliográficos
Main Authors: Waning, David L., Russell, Charles J., Jardetzky, Theodore S., Lamb, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC438956/
https://ncbi.nlm.nih.gov/pubmed/15197264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403339101
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