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Polybasic KKR Motif in the Cytoplasmic Tail of Nipah Virus Fusion Protein Modulates Membrane Fusion by Inside-Out Signaling

The cytoplasmic tails of the envelope proteins from multiple viruses are known to contain determinants that affect their fusogenic capacities. Here we report that specific residues in the cytoplasmic tail of the Nipah virus fusion protein (NiV-F) modulate its fusogenic activity. Truncation of the cy...

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Autors principals: Aguilar, Hector C., Matreyek, Kenneth A., Choi, Daniel Y., Filone, Claire Marie, Young, Sophia, Lee, Benhur
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900187/
https://ncbi.nlm.nih.gov/pubmed/17301148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02205-06
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