Large-scale determination of absolute phosphorylation stoichiometries in human cells by motif-targeting quantitative proteomics

Our ability to model the dynamics of signal transduction networks will depend on accurate methods to quantify levels of protein phosphorylation on a global scale. Here we describe a motif-targeting quantitation method for phosphorylation stoichiometry typing. Proteome-wide phosphorylation stoichiome...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Tsai, Chia-Feng, Wang, Yi-Ting, Yen, Hsin-Yung, Tsou, Chih-Chiang, Ku, Wei-Chi, Lin, Pei-Yi, Chen, Hsuan-Yu, Nesvizhskii, Alexey I., Ishihama, Yasushi, Chen, Yu-Ju
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389224/
https://ncbi.nlm.nih.gov/pubmed/25814448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7622
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