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Untargeted, spectral library-free analysis of data independent acquisition proteomics data generated using Orbitrap mass spectrometers

We describe an improved version of the data independent acquisition (DIA) computational analysis tool DIA-Umpire, and show that it enables highly sensitive, untargeted and direct (spectral library-free) analysis of DIA data obtained using the Orbitrap family of mass spectrometers. DIA-Umpire v2 impl...

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書目詳細資料
發表在:Proteomics
Main Authors: Tsou, Chih-Chiang, Tsai, Chia-Feng, Teo, Guoci, Chen, Yu-Ju, Nesvizhskii, Alexey I.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476226/
https://ncbi.nlm.nih.gov/pubmed/27246681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201500526
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