High Expression of KCa3.1 in Patients with Clear Cell Renal Carcinoma Predicts High Metastatic Risk and Poor Survival

BACKGROUND: Ca(2+)-activated K(+) channels have been implicated in cancer cell growth, metastasis, and tumor angiogenesis. Here we hypothesized that high mRNA and protein expression of the intermediate-conductance Ca(2+)-activated K(+) channel, KCa3.1, is a molecular marker of clear cell Renal Cell...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rabjerg, Maj, Oliván-Viguera, Aida, Hansen, Lars Koch, Jensen, Line, Sevelsted-Møller, Linda, Walter, Steen, Jensen, Boye L., Marcussen, Niels, Köhler, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388734/
https://ncbi.nlm.nih.gov/pubmed/25848765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122992
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