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Expression of CDK1(Tyr15), pCDK1(Thr161), Cyclin B1 (Total) and pCyclin B1(Ser126) in Vulvar Squamous Cell Carcinoma and Their Relations with Clinicopatological Features and Prognosis

Cyclin B1-CDK1 complex plays an important role in the regulation of cell cycle. Activation of Cyclin B1 and CDK1 and the formation of the complex in G2/M are under multiple regulations involving many regulators such as isoforms of 14-3-3 and CDC25 and Wee1. Abnormal expression of Cyclin B1 and CDK1...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Wang, Zhihui, Slipicevic, Ana, Førsund, Mette, Trope, Claes G., Nesland, Jahn M., Holm, Ruth
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388712/
https://ncbi.nlm.nih.gov/pubmed/25849598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121398
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