Increase of microRNA-210, Decrease of Raptor Gene Expression and Alteration of Mammalian Target of Rapamycin Regulated Proteins following Mithramycin Treatment of Human Erythroid Cells

Expression and regulation of microRNAs is an emerging issue in erythroid differentiation and globin gene expression in hemoglobin disorders. In the first part of this study microarray analysis was performed both in mithramycin-induced K562 cells and erythroid precursors from healthy subjects or β-th...

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Veröffentlicht in:PLoS One
Hauptverfasser: Bianchi, Nicoletta, Finotti, Alessia, Ferracin, Manuela, Lampronti, Ilaria, Zuccato, Cristina, Breveglieri, Giulia, Brognara, Eleonora, Fabbri, Enrica, Borgatti, Monica, Negrini, Massimo, Gambari, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388523/
https://ncbi.nlm.nih.gov/pubmed/25849663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121567
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