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The crystal structure of phosphorylated MAPK13 reveals common structural features and differences in p38 MAPK family activation

The p38 MAP kinases (p38 MAPKs) represent an important family centrally involved in mediating extracellular signaling. Recent studies indicate that family members such as MAPK13 (p38δ) display a selective cellular and tissue expression and are therefore involved in specific diseases. Detailed struct...

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Veröffentlicht in:Acta Crystallogr D Biol Crystallogr
Hauptverfasser: Yurtsever, Zeynep, Scheaffer, Suzanne M., Romero, Arthur G., Holtzman, Michael J., Brett, Tom J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388263/
https://ncbi.nlm.nih.gov/pubmed/25849390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715001212
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