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The crystal structure of phosphorylated MAPK13 reveals common structural features and differences in p38 MAPK family activation

The p38 MAP kinases (p38 MAPKs) represent an important family centrally involved in mediating extracellular signaling. Recent studies indicate that family members such as MAPK13 (p38δ) display a selective cellular and tissue expression and are therefore involved in specific diseases. Detailed struct...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr D Biol Crystallogr
Main Authors: Yurtsever, Zeynep, Scheaffer, Suzanne M., Romero, Arthur G., Holtzman, Michael J., Brett, Tom J.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388263/
https://ncbi.nlm.nih.gov/pubmed/25849390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715001212
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