B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) characterized by autoimmune mediated demyelination and neurodegeneration. The CNS of patients with MS harbors expanded clones of antigen-experienced B cells that reside in distinct compartments including the menin...

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Publicado no:Sci Transl Med
Main Authors: Stern, Joel N. H., Yaari, Gur, Vander Heiden, Jason A., Church, George, Donahue, William F., Hintzen, Rogier Q., Huttner, Anita J., Laman, Jon D., Nagra, Rashed M., Nylander, Alyssa, Pitt, David, Ramanan, Sriram, Siddiqui, Bilal A., Vigneault, Francois, Kleinstein, Steven H., Hafler, David A., O’Connor, Kevin C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388137/
https://ncbi.nlm.nih.gov/pubmed/25100741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008879
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