Antibody-mediated targeting of iron oxide nanoparticles to the folate receptor alpha increases tumor cell association in vitro and in vivo

Active molecular targeting has become an important aspect of nanoparticle development for oncology indications. Here, we describe molecular targeting of iron oxide nanoparticles (IONPs) to the folate receptor alpha (FOLRα) using an engineered antibody fragment (Ffab). Compared to control nanoparticl...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Int J Nanomedicine
Auteurs principaux: Ndong, Christian, Toraya-Brown, Seiko, Kekalo, Katsiaryna, Baker, Ian, Gerngross, Tillman U, Fiering, Steven N, Griswold, Karl E
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2015
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388088/
https://ncbi.nlm.nih.gov/pubmed/25878495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S79367
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires