Tumor Cell Targeting by Iron Oxide Nanoparticles Is Dominated by Different Factors In Vitro versus In Vivo

Realizing the full potential of iron oxide nanoparticles (IONP) for cancer diagnosis and therapy requires selective tumor cell accumulation. Here, we report a systematic analysis of two key determinants for IONP homing to human breast cancers: (i) particle size and (ii) active vs passive targeting....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: NDong, Christian, Tate, Jennifer A., Kett, Warren C., Batra, Jaya, Demidenko, Eugene, Lewis, Lionel D., Hoopes, P. Jack, Gerngross, Tillman U., Griswold, Karl E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335054/
https://ncbi.nlm.nih.gov/pubmed/25695795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115636
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