Suppressed autophagy flux in skeletal muscle of an amyotrophic lateral sclerosis mouse model during disease progression

Accumulation of abnormal protein inclusions is implicated in motor neuron degeneration in amyotrophic lateral sclerosis (ALS). Autophagy, an intracellular process targeting misfolded proteins and damaged organelles for lysosomal degradation, plays crucial roles in survival and diseased conditions. E...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Physiol Rep
Egile Nagusiak: Xiao, Yajuan, Ma, Changling, Yi, Jianxun, Wu, Shaoping, Luo, Guo, Xu, Xiulong, Lin, Pei‐Hui, Sun, Jun, Zhou, Jingsong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Wiley Periodicals, Inc. 2015
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387765/
https://ncbi.nlm.nih.gov/pubmed/25602021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12271
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