Activin/Nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions by controlling the H3K4me3 chromatin mark

Stem cells can self-renew and differentiate into multiple cell types. These characteristics are maintained by the combination of specific signaling pathways and transcription factors that cooperate to establish a unique epigenetic state. Despite the broad interest of these mechanisms, the precise mo...

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Bibliographische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Bertero, Alessandro, Madrigal, Pedro, Galli, Antonella, Hubner, Nina C., Moreno, Inmaculada, Burks, Deborah, Brown, Stephanie, Pedersen, Roger A., Gaffney, Daniel, Mendjan, Sasha, Pauklin, Siim, Vallier, Ludovic
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2015
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387713/
https://ncbi.nlm.nih.gov/pubmed/25805847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.255984.114
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