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Autoinhibitory mechanisms of ERG studied by molecular dynamics simulations
ERG, an ETS-family transcription factor, acts as a regulator of differentiation of early hematopoietic cells. It contains an autoinhibitory domain, which negatively regulates DNA-binding. The mechanism of autoinhibitory is still illusive. To understand the mechanism, we study the dynamical propertie...
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| Опубликовано в: : | AIP Adv |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
AIP Publishing LLC
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4387600/ https://ncbi.nlm.nih.gov/pubmed/25874157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4906572 |
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