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Pharmacological stress is required for the anti-alcohol effect of the α3β4* nAChR partial agonist AT-1001

Alcohol and nicotine are often taken together. The mechanisms underlying this frequent co-abuse are not well known. Genetic and pharmacological evidence suggests that the nicotinic acetylcholine receptors (nAChRs) containing the α3 and β4 subunits play a role in alcohol as well as nicotine addiction...

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Bibliographische Detailangaben
Veröffentlicht in:Neuropharmacology
Hauptverfasser: Cippitelli, Andrea, Brunori, Gloria, Gaiolini, Kelly A., Zaveri, Nurulain T., Toll, Lawrence
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387088/
https://ncbi.nlm.nih.gov/pubmed/25689019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.02.005
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